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Nov 30, 1999
Screening Implementation in Middle - and Low-income Countries
Dominic Rothwell
United Kingdom
Dominic Rothwell
Speaker of: Screening Implementation in Middle - and Low-income Countries
Dr Dominic Graham Rothwell. NAB Team Leader, Cancer Research UK Manchester Institute Cancer Biomarker Centre, University of Manchester, UK.
After obtaining a BSc (Hon) in Applied Genetics from the University of Liverpool I studied for my DPhil with Professor Ian Hickson at the Weatherall Institute, University of Oxford investigating the functional role DNA repair genes. After this I moved into more translational research, initially with Dr John Norton looking for molecular markers in multiple myeloma before joining Professor Robert Hawkins laboratory at the University of Manchester where I was responsible for developing molecular monitoring of immunotherapy trials including CAR T-cells and the establishment of a GCP compliant facility. In 2011 I joined the Nucleic Acid Biomarker (NAB) team of Professor Caroline Dive at the CRUK Manchester Institute and began my current research focus on the molecular analysis of blood borne biomarkers for use in cancer. This work focusses on utilising circulating free DNA (cfDNA) and circulating tumour cells (CTC) to enable the molecular characterisation of tumours at the genetic, epigenetic and transcriptional level from a patient blood sample. I took over as Team Leader of NAB in November 2019.
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