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Nov 30, 1999
Sex Differences in Lung Cancer Screening
Julien Sage
USA
Julien Sage
Speaker of: Sex Differences in Lung Cancer Screening
Dr. Sage trained at the University of Nice (PhD) in France and MIT (post-doc) before starting his research group at Stanford University in 2004. He is currently the Elaine and John Chambers Professor of Pediatric Cancer at Stanford and serves as the co-Director of the Cancer Biology PhD program. The Sage lab is fundamentally interested in the mechanism driving the proliferation of cells. Dr. Sage has been working for many years now on the RB tumor suppressor and how loss of RB promotes tumorigenesis in children and adult patients. Dr. Sage became initially interested in small cell lung cancer (SCLC) because of the nearly ubiquitous loss of RB in this cancer type and the intriguing relationship in mice and humans between loss of RB and the growth of neuroendocrine lesions. In the past few years, the Sage lab has developed pre-clinical models for SCLC and has used these models to investigate signaling pathways driving the growth of this cancer type as well as the mechanisms underlying how SCLC tumors become resistant to therapy.
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