|
Nov 30, 1999
Early Detection of Interstitial and Obstructive Lung Diseases
Anish Thomas
USA
Anish Thomas
Speaker of: Early Detection of Interstitial and Obstructive Lung Diseases
Anish Thomas is a clinical researcher and thoracic oncologist. The goals of his research program are: 1) to develop more effective therapies for patients with SCLC by targeting DNA replication, repair, and chromatin remodeling, and 2) genomic characterization of SCLCs to better understand the basis of treatment response and resistance. Work from his group has revealed replication stress as a transformative vulnerability of SCLCs characterized by high neuroendocrine differentiation, targetable by ATR inhibition (PMID: 33848478; PMID: 29252124), provided novel insights into the transcriptomic features that render low neuroendocrine SCLC more sensitive to immunotherapy (PMID: 34162872), and discovered a novel SCLC subset defined by the germline genotype and improved responses to DNA repair targeted drugs (PMID: 33504652).
The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ISLB. The mention of any product, service, organization, activity, or therapy should not be construed as an ISLB endorsement.
Recent Episodes
Nov 01, 2025
Nov 23, 2024
Nov 21, 2023
Nov 30, 1999
David MacPherson
Nov 30, 1999
Kate Sutherland
Nov 30, 1999
Portia Thomas
Nov 30, 1999
Simon Heeke
Nov 30, 1999
Bruno Paiva
Nov 30, 1999
Catherine Meador
Nov 30, 1999
Carmen Garrido
Nov 30, 1999
Heather Wakelee
